STEM 101’s high school curriculum represents a blended learning, project-based experience that is accessible from any Web-enabled device. Students are actively engaged in hands-on, minds-on activities through which they realize the application and relevance of their STEM education experience. It is recommended that schools get started by establishing a STEM literacy platform for all students with the STEM 101’s high school foundation curriculum repository. This repository includes the following courses: Introduction to Engineering and Principles of Engineering. High school career pathways are featured for architecture, engineering, environmental, manufacturing, medical, renewable energy, science and technology. Schools may opt for individual course integration. STEM 101’s curriculum is based on national standards featuring correlation to individual state standards. The flexible use curriculum design produces a meta-disciplinary STEM education practice through which all faculty and students are engaged. STEM 101 high school curriculum can be utilized for in-school, after-school and summer bridge programming. Curriculum units include learning objectives, teacher resources, content knowledge, student activity, STEM connections and assessments.